CEL - Affymetrix Probe Results File

What is a CEL file

Affimetrix developed a DNA image analysis program that makes use of so-called CEL files. The file contains all kinds of data that is gathered from probes. This data is stored on a specific GeneChip that can hold a multitude of different data. Thus CEL files usually have a quite big file size. The CEL files can be used to generate a 2D grid or graphic of a genome after analyzing and visualizing the data inside the file.

Usually, one GeneChip is used per experiment. They are generated out of silicone or glass and contain the probe. The data found in these probes with regard to matching and mismatching values are stored in the CEL file format. They are especially used in the research of diseases in both animals and humans since the data can show alterations in the DNA of the recorded probe. CEL files are saved in both a binary and ASCII format, depending on the version of the file. Furthermore, a CEL file can only be used with the respective CDF file. The CDF file stores a dictionary that is specific to the probe data of the CEL file.

Here's a small, but not exhaustive list of programs that can open CEL documents:

  • Affymetrix Tiling Analysis Software (Windows)
  • dChip (Windows)
  • multi-aff-py (Windows, Mac & Linux)
  • RMAExpress (Windows)
  • The MathWorks MATLAB (Windows)
  • VSN GenStat (Windows)
Extension CEL
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